Cargando…
Regulation of brain insulin signaling: A new function for tau
In this issue of JEM, Marciniak et al. (https://doi.org/10.1084/jem.20161731) identify a putative novel function of tau protein as a regulator of insulin signaling in the brain. They find that tau deletion impairs hippocampal response to insulin through IRS-1 and PTEN dysregulation and suggest that,...
Autores principales: | Gratuze, Maud, Planel, Emmanuel |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5551584/ https://www.ncbi.nlm.nih.gov/pubmed/28652305 http://dx.doi.org/10.1084/jem.20170979 |
Ejemplares similares
-
Insulin dysfunction and Tau pathology
por: El Khoury, Noura B., et al.
Publicado: (2014) -
Insulin deprivation induces PP2A inhibition and tau hyperphosphorylation in hTau mice, a model of Alzheimer’s disease-like tau pathology
por: Gratuze, Maud, et al.
Publicado: (2017) -
Insulin resistance and obesity: how do they affect tau pathology?
por: Gratuze, Maud, et al.
Publicado: (2013) -
Arterial Stiffness Due to Carotid Calcification Disrupts Cerebral Blood Flow Regulation and Leads to Cognitive Deficits
por: Muhire, Gervais, et al.
Publicado: (2019) -
Parenchymal border macrophages regulate tau pathology and tau-mediated neurodegeneration
por: Drieu, Antoine, et al.
Publicado: (2023)