The G protein–coupled receptor GPR31 promotes membrane association of KRAS

The product of the KRAS oncogene, KRAS4B, promotes tumor growth when associated with the plasma membrane (PM). PM association is mediated, in part, by farnesylation of KRAS4B, but trafficking of nascent KRAS4B to the PM is incompletely understood. We performed a genome-wide screen to identify genes...

Descripción completa

Detalles Bibliográficos
Autores principales: Fehrenbacher, Nicole, Tojal da Silva, Israel, Ramirez, Craig, Zhou, Yong, Cho, Kwang-Jin, Kuchay, Shafi, Shi, Jie, Thomas, Susan, Pagano, Michele, Hancock, John F., Bar-Sagi, Dafna, Philips, Mark R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5551702/
https://www.ncbi.nlm.nih.gov/pubmed/28619714
http://dx.doi.org/10.1083/jcb.201609096

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5551702/
https://www.ncbi.nlm.nih.gov/pubmed/28619714
http://dx.doi.org/10.1083/jcb.201609096

Ejemplares similares