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Pink1 and Parkin regulate Drosophila intestinal stem cell proliferation during stress and aging
Intestinal stem cells (ISCs) maintain the midgut epithelium in Drosophila melanogaster. Proper cellular turnover and tissue function rely on tightly regulated rates of ISC division and appropriate differentiation of daughter cells. However, aging and epithelial injury cause elevated ISC proliferatio...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5551703/ https://www.ncbi.nlm.nih.gov/pubmed/28663346 http://dx.doi.org/10.1083/jcb.201610036 |