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Pink1 and Parkin regulate Drosophila intestinal stem cell proliferation during stress and aging

Intestinal stem cells (ISCs) maintain the midgut epithelium in Drosophila melanogaster. Proper cellular turnover and tissue function rely on tightly regulated rates of ISC division and appropriate differentiation of daughter cells. However, aging and epithelial injury cause elevated ISC proliferatio...

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Detalles Bibliográficos
Autores principales:	Koehler, Christopher L., Perkins, Guy A., Ellisman, Mark H., Jones, D. Leanne
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2017
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5551703/ https://www.ncbi.nlm.nih.gov/pubmed/28663346 http://dx.doi.org/10.1083/jcb.201610036

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