ER stress causes widespread protein aggregation and prion formation

Disturbances in endoplasmic reticulum (ER) homeostasis create a condition termed ER stress. This activates the unfolded protein response (UPR), which alters the expression of many genes involved in ER quality control. We show here that ER stress causes the aggregation of proteins, most of which are...

Descripción completa

Detalles Bibliográficos
Autores principales: Hamdan, Norfadilah, Kritsiligkou, Paraskevi, Grant, Chris M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5551711/
https://www.ncbi.nlm.nih.gov/pubmed/28630146
http://dx.doi.org/10.1083/jcb.201612165

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5551711/
https://www.ncbi.nlm.nih.gov/pubmed/28630146
http://dx.doi.org/10.1083/jcb.201612165

Ejemplares similares