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Activity-dependent trafficking of lysosomes in dendrites and dendritic spines

In neurons, lysosomes, which degrade membrane and cytoplasmic components, are thought to primarily reside in somatic and axonal compartments, but there is little understanding of their distribution and function in dendrites. Here, we used conventional and two-photon imaging and electron microscopy t...

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Detalles Bibliográficos
Autores principales: Goo, Marisa S., Sancho, Laura, Slepak, Natalia, Boassa, Daniela, Deerinck, Thomas J., Ellisman, Mark H., Bloodgood, Brenda L., Patrick, Gentry N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5551717/
https://www.ncbi.nlm.nih.gov/pubmed/28630145
http://dx.doi.org/10.1083/jcb.201704068