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Effect of teriflunomide on cortex-basal ganglia-thalamus (CxBGTh) circuit glutamatergic dysregulation in the Theiler's Murine Encephalomyelitis Virus mouse model of multiple sclerosis

BACKGROUND: Pathology of gray matter is associated with development of physical and cognitive disability in patients with multiple sclerosis. In particular, glutamatergic dysregulation in the cortex-basal ganglia-thalamus (CxBGTh) circuit could be associated with decline in these behaviors. OBJECTIV...

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Detalles Bibliográficos
Autores principales: Modica, Claire M., Schweser, Ferdinand, Sudyn, Michelle L., Bertolino, Nicola, Preda, Marilena, Polak, Paul, Siebert, Danielle M., Krawiecki, Jacqueline C., Sveinsson, Michele, Hagemeier, Jesper, Dwyer, Michael G., Pol, Suyog, Zivadinov, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5552032/
https://www.ncbi.nlm.nih.gov/pubmed/28796815
http://dx.doi.org/10.1371/journal.pone.0182729