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Minimal Purkinje Cell-Specific PCP2/L7 Promoter Virally Available for Rodents and Non-human Primates

Cell-type-specific promoters in combination with viral vectors and gene-editing technology permit efficient gene manipulation in specific cell populations. Cerebellar Purkinje cells play a pivotal role in cerebellar functions. Although the Purkinje cell-specific L7 promoter is widely used for the ge...

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Detalles Bibliográficos
Autores principales: Nitta, Keisuke, Matsuzaki, Yasunori, Konno, Ayumu, Hirai, Hirokazu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5552061/
https://www.ncbi.nlm.nih.gov/pubmed/28828391
http://dx.doi.org/10.1016/j.omtm.2017.07.006