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Unfolding of core nucleosomes by PARP-1 revealed by spFRET microscopy

DNA accessibility to various protein complexes is essential for various processes in the cell and is affected by nucleosome structure and dynamics. Protein factor PARP-1 (poly(ADP-ribose) polymerase 1) increases the accessibility of DNA in chromatin to repair proteins and transcriptional machinery,...

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Detalles Bibliográficos
Autores principales: Sultanov, Daniel, Gerasimova, Nadezhda, Kudryashova, Kseniya, Maluchenko, Natalya, Kotova, Elena, Langelier, Marie-France, Pascal, John, Kirpichnikov, Mikhail, Feofanov, Alexey, Studitsky, Vasily
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AIMS Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5552189/
https://www.ncbi.nlm.nih.gov/pubmed/28804761
http://dx.doi.org/10.3934/genet.2017.1.21