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A Multistage Subunit Vaccine Effectively Protects Mice Against Primary Progressive Tuberculosis, Latency and Reactivation

Adult tuberculosis (TB) is the main cause of TB epidemic and death. The infection results mainly by endogenous reactivation of latent TB infection and secondarily transmitted by exogenous infection. There is no vaccine for adult TB. To this end, we first chose antigens from a potential antigenic res...

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Detalles Bibliográficos
Autores principales: Ma, Jilei, Teng, Xindong, Wang, Xiaochun, Fan, Xionglin, Wu, Yaqi, Tian, Maopeng, Zhou, Zijie, Li, Longmeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5552207/
https://www.ncbi.nlm.nih.gov/pubmed/28711483
http://dx.doi.org/10.1016/j.ebiom.2017.07.005