Single nucleotide polymorphisms associated with P2X7R function regulate the onset of gouty arthritis

BACKGROUND: Gout is an inflammatory disease that is caused by the increased production of Interleukin-1β (IL-1β) stimulated by monosodium urate (MSU) crystals. However, some hyperuricemia patients, even gouty patients with tophi in the joints, never experience gout attack, which indicates that patho...

Descripción completa

Detalles Bibliográficos
Autores principales: Tao, Jin-Hui, Cheng, Miao, Tang, Jiang-Ping, Dai, Xiao-Juan, Zhang, Yong, Li, Xiang-Pei, Liu, Qin, Wang, Ya-Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5552250/
https://www.ncbi.nlm.nih.gov/pubmed/28797095
http://dx.doi.org/10.1371/journal.pone.0181685

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5552250/
https://www.ncbi.nlm.nih.gov/pubmed/28797095
http://dx.doi.org/10.1371/journal.pone.0181685

Ejemplares similares