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Single nucleotide polymorphisms associated with P2X7R function regulate the onset of gouty arthritis
BACKGROUND: Gout is an inflammatory disease that is caused by the increased production of Interleukin-1β (IL-1β) stimulated by monosodium urate (MSU) crystals. However, some hyperuricemia patients, even gouty patients with tophi in the joints, never experience gout attack, which indicates that patho...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5552250/ https://www.ncbi.nlm.nih.gov/pubmed/28797095 http://dx.doi.org/10.1371/journal.pone.0181685 |