ATP Maintenance via Two Types of ATP Regulators Mitigates Pathological Phenotypes in Mouse Models of Parkinson's Disease

Parkinson's disease is assumed to be caused by mitochondrial dysfunction in the affected dopaminergic neurons in the brain. We have recently created small chemicals, KUSs (Kyoto University Substances), which can reduce cellular ATP consumption. By contrast, agonistic ligands of ERRs (estrogen r...

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Detalles Bibliográficos
Autores principales: Nakano, Masaki, Imamura, Hiromi, Sasaoka, Norio, Yamamoto, Masamichi, Uemura, Norihito, Shudo, Toshiyuki, Fuchigami, Tomohiro, Takahashi, Ryosuke, Kakizuka, Akira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5552266/
https://www.ncbi.nlm.nih.gov/pubmed/28780078
http://dx.doi.org/10.1016/j.ebiom.2017.07.024

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5552266/
https://www.ncbi.nlm.nih.gov/pubmed/28780078
http://dx.doi.org/10.1016/j.ebiom.2017.07.024

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