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Gender difference in NASH susceptibility: Roles of hepatocyte Ikkβ and Sult1e1

Myeloid cell and hepatocyte IKKβ may mediate the genesis of obesity and insulin resistance in mice fed high fat diet. However, their gender-specific roles in the pathogenesis of non-alcoholic steatohepatitis (NASH) are not known. Here we demonstrate myeloid IKKβ deficiency prevents Western diet-indu...

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Detalles Bibliográficos
Autores principales: Matsushita, Noriko, Hassanein, Mohamed T., Martinez-Clemente, Marcos, Lazaro, Raul, French, Samuel W., Xie, Wen, Lai, Keane, Karin, Michael, Tsukamoto, Hidekazu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5552280/
https://www.ncbi.nlm.nih.gov/pubmed/28797077
http://dx.doi.org/10.1371/journal.pone.0181052