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Calcium imaging with genetically encoded sensor Case12: Facile analysis of α7/α9 nAChR mutants

Elucidation of the structural basis of pharmacological differences for highly homologous α7 and α9 nicotinic acetylcholine receptors (nAChRs) may shed light on their involvement in different physiological functions and diseases. Combination of site-directed mutagenesis and electrophysiology is a pow...

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Detalles Bibliográficos
Autores principales: Shelukhina, Irina, Spirova, Ekaterina, Kudryavtsev, Denis, Ojomoko, Lucy, Werner, Markus, Methfessel, Christoph, Hollmann, Michael, Tsetlin, Victor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5552293/
https://www.ncbi.nlm.nih.gov/pubmed/28797116
http://dx.doi.org/10.1371/journal.pone.0181936