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Calcium imaging with genetically encoded sensor Case12: Facile analysis of α7/α9 nAChR mutants
Elucidation of the structural basis of pharmacological differences for highly homologous α7 and α9 nicotinic acetylcholine receptors (nAChRs) may shed light on their involvement in different physiological functions and diseases. Combination of site-directed mutagenesis and electrophysiology is a pow...
Autores principales: | Shelukhina, Irina, Spirova, Ekaterina, Kudryavtsev, Denis, Ojomoko, Lucy, Werner, Markus, Methfessel, Christoph, Hollmann, Michael, Tsetlin, Victor |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5552293/ https://www.ncbi.nlm.nih.gov/pubmed/28797116 http://dx.doi.org/10.1371/journal.pone.0181936 |
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