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Increased microRNA-93-5p inhibits osteogenic differentiation by targeting bone morphogenetic protein-2

BACKGROUND AND PURPOSE: Trauma-induced osteonecrosis of the femoral head (TIONFH) is a major complication of femoral neck fractures. Degeneration and necrosis of subchondral bone can cause collapse, which results in hip joint dysfunction in patients. The destruction of bone metabolism homeostasis is...

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Detalles Bibliográficos
Autores principales: Zhang, Ying, Wei, Qiu-Shi, Ding, Wei-Bin, Zhang, Lei-Lei, Wang, Hui-Chao, Zhu, Ying-Jie, He, Wei, Chai, Yu-Na, Liu, You-Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5552299/
https://www.ncbi.nlm.nih.gov/pubmed/28797104
http://dx.doi.org/10.1371/journal.pone.0182678