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Jasplakinolide induces primary cilium formation through cell rounding and YAP inactivation

Primary cilia are non-motile cilia that serve as cellular antennae for sensing and transducing extracellular signals. In general, primary cilia are generated by cell quiescence signals. Recent studies have shown that manipulations to increase actin assembly suppress quiescence-induced ciliogenesis....

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Detalles Bibliográficos
Autores principales: Nagai, Tomoaki, Mizuno, Kensaku
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5552318/
https://www.ncbi.nlm.nih.gov/pubmed/28797107
http://dx.doi.org/10.1371/journal.pone.0183030