HIV-1 infection depletes human CD34(+)CD38(-) hematopoietic progenitor cells via pDC-dependent mechanisms

Chronic human immunodeficiency virus-1 (HIV-1) infection in patients leads to multi-lineage hematopoietic abnormalities or pancytopenia. The deficiency in hematopoietic progenitor cells (HPCs) induced by HIV-1 infection has been proposed, but the relevant mechanisms are poorly understood. We report...

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Detalles Bibliográficos
Autores principales: Li, Guangming, Zhao, Juanjuan, Cheng, Liang, Jiang, Qi, Kan, Sheng, Qin, Enqiang, Tu, Bo, Zhang, Xin, Zhang, Liguo, Su, Lishan, Zhang, Zheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5552321/
https://www.ncbi.nlm.nih.gov/pubmed/28759657
http://dx.doi.org/10.1371/journal.ppat.1006505

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5552321/
https://www.ncbi.nlm.nih.gov/pubmed/28759657
http://dx.doi.org/10.1371/journal.ppat.1006505

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