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HIV-1 infection depletes human CD34(+)CD38(-) hematopoietic progenitor cells via pDC-dependent mechanisms
Chronic human immunodeficiency virus-1 (HIV-1) infection in patients leads to multi-lineage hematopoietic abnormalities or pancytopenia. The deficiency in hematopoietic progenitor cells (HPCs) induced by HIV-1 infection has been proposed, but the relevant mechanisms are poorly understood. We report...
Autores principales: | Li, Guangming, Zhao, Juanjuan, Cheng, Liang, Jiang, Qi, Kan, Sheng, Qin, Enqiang, Tu, Bo, Zhang, Xin, Zhang, Liguo, Su, Lishan, Zhang, Zheng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5552321/ https://www.ncbi.nlm.nih.gov/pubmed/28759657 http://dx.doi.org/10.1371/journal.ppat.1006505 |
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