The tetraspanin CD9 facilitates MERS-coronavirus entry by scaffolding host cell receptors and proteases
Infection by enveloped coronaviruses (CoVs) initiates with viral spike (S) proteins binding to cellular receptors, and is followed by proteolytic cleavage of receptor-bound S proteins, which prompts S protein-mediated virus-cell membrane fusion. Infection therefore requires close proximity of recept...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5552337/ https://www.ncbi.nlm.nih.gov/pubmed/28759649 http://dx.doi.org/10.1371/journal.ppat.1006546 |