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Anaplasma phagocytophilum infection modulates expression of megakaryocyte cell cycle genes through phosphatidylinositol-3-kinase signaling

Anaplasma phagocytophilum, the agent of human granulocytic anaplasmosis infects neutrophils and other cells from hematopoietic origin. Using human megakaryocytic cell line, MEG-01, we show that expression of cell cycle genes in these cells are altered upon A. phagocytophilum infection. Expression of...

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Detalles Bibliográficos
Autores principales: Khanal, Supreet, Sultana, Hameeda, Catravas, John D., Carlyon, Jason A., Neelakanta, Girish
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5552339/
https://www.ncbi.nlm.nih.gov/pubmed/28797056
http://dx.doi.org/10.1371/journal.pone.0182898