Dynactin binding to tyrosinated microtubules promotes centrosome centration in C. elegans by enhancing dynein-mediated organelle transport

The microtubule-based motor dynein generates pulling forces for centrosome centration and mitotic spindle positioning in animal cells. How the essential dynein activator dynactin regulates these functions of the motor is incompletely understood. Here, we dissect the role of dynactin's microtubu...

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Detalles Bibliográficos
Autores principales: Barbosa, Daniel J., Duro, Joana, Prevo, Bram, Cheerambathur, Dhanya K., Carvalho, Ana X., Gassmann, Reto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5552355/
https://www.ncbi.nlm.nih.gov/pubmed/28759579
http://dx.doi.org/10.1371/journal.pgen.1006941

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5552355/
https://www.ncbi.nlm.nih.gov/pubmed/28759579
http://dx.doi.org/10.1371/journal.pgen.1006941

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