HBEGF promotes gliomagenesis in the context of Ink4a/Arf and Pten loss

Heparin-binding epidermal growth factor (EGF)-like growth factor (HBEGF) is a ligand for the epidermal growth factor receptor (EGFR), one of the most commonly amplified receptor tyrosine kinases (RTK) in glioblastoma. While HBEGF has been found to be expressed in a subset of malignant gliomas, its s...

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Detalles Bibliográficos
Autores principales: Shin, Clifford H., Robinson, James P., Sonnen, Joshua A., Welker, Adam E., Yu, Diana X., VanBrocklin, Matthew W., Holmen, Sheri L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5552427/
https://www.ncbi.nlm.nih.gov/pubmed/28368403
http://dx.doi.org/10.1038/onc.2017.83

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5552427/
https://www.ncbi.nlm.nih.gov/pubmed/28368403
http://dx.doi.org/10.1038/onc.2017.83

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