Myc enhances B cell receptor signaling in precancerous B cells and confers resistance to Btk inhibition

Dysregulation of the oncogenic transcription factor MYC induces B cell transformation and is a driver for B cell non-Hodgkin lymphoma (B-NHL). MYC overexpression in B-NHL is associated with more aggressive phenotypes and poor prognosis. Although genomic studies suggest a link between MYC overexpress...

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Detalles Bibliográficos
Autores principales: Moyo, Tamara K., Wilson, Christopher S., Moore, Daniel J., Eischen, Christine M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5552428/
https://www.ncbi.nlm.nih.gov/pubmed/28368423
http://dx.doi.org/10.1038/onc.2017.95

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5552428/
https://www.ncbi.nlm.nih.gov/pubmed/28368423
http://dx.doi.org/10.1038/onc.2017.95

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