Down-Regulation of TGF-β Expression Sensitizes the Resistance of Hepatocellular Carcinoma Cells to Sorafenib

PURPOSE: Sorafenib, a multikinase inhibitor, is the standard therapy for patients with advanced-stage hepatocellular carcinoma (HCC). However, resistance develops to the treatment, therefore, we tried to unravel the underlying mechanism in the resistance of HCC cells to sorafenib via the development...

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Detalles Bibliográficos
Autores principales: Kang, Dongxu, Han, Zhezhu, Oh, Geun-Hyeok, Joo, Yeonsoo, Choi, Hye Jin, Song, Jae J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Yonsei University College of Medicine 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5552643/
https://www.ncbi.nlm.nih.gov/pubmed/28792132
http://dx.doi.org/10.3349/ymj.2017.58.5.899

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5552643/
https://www.ncbi.nlm.nih.gov/pubmed/28792132
http://dx.doi.org/10.3349/ymj.2017.58.5.899

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