Cargando…
Down-Regulation of TGF-β Expression Sensitizes the Resistance of Hepatocellular Carcinoma Cells to Sorafenib
PURPOSE: Sorafenib, a multikinase inhibitor, is the standard therapy for patients with advanced-stage hepatocellular carcinoma (HCC). However, resistance develops to the treatment, therefore, we tried to unravel the underlying mechanism in the resistance of HCC cells to sorafenib via the development...
Autores principales: | Kang, Dongxu, Han, Zhezhu, Oh, Geun-Hyeok, Joo, Yeonsoo, Choi, Hye Jin, Song, Jae J. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Yonsei University College of Medicine
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5552643/ https://www.ncbi.nlm.nih.gov/pubmed/28792132 http://dx.doi.org/10.3349/ymj.2017.58.5.899 |
Ejemplares similares
-
TGF-β downregulation-induced cancer cell death is finely regulated by the SAPK signaling cascade
por: Han, Zhezhu, et al.
Publicado: (2018) -
Prime-boost immunization by both DNA vaccine and oncolytic adenovirus expressing GM-CSF and shRNA of TGF-β2 induces anti-tumor immune activation
por: Kim, So Young, et al.
Publicado: (2017) -
High levels of Daxx due to low cellular levels of HSP25 in murine cancer cells result in inefficient adenovirus replication
por: Han, Zhezhu, et al.
Publicado: (2019) -
Combined Inhibition of TGF-β1-Induced EMT and PD-L1 Silencing Re-Sensitizes Hepatocellular Carcinoma to Sorafenib Treatment
por: Shrestha, Ritu, et al.
Publicado: (2021) -
Glutamine synthetase mediates sorafenib sensitivity in β-catenin-active hepatocellular carcinoma cells
por: Sohn, Bo Hwa, et al.
Publicado: (2018)