Luciferase Expression Allows Bioluminescence Imaging But Imposes Limitations on the Orthotopic Mouse (4T1) Model of Breast Cancer

Implantation of reporter-labeled tumor cells in an immunocompetent host involves a risk of their immune elimination. We have studied this effect in a mouse model of breast cancer after the orthotopic implantation of mammary gland adenocarcinoma 4T1 cells genetically labelled with luciferase (Luc). M...

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Detalles Bibliográficos
Autores principales: Baklaushev, V. P., Kilpeläinen, A., Petkov, S., Abakumov, M. A., Grinenko, N. F., Yusubalieva, G. M., Latanova, A. A., Gubskiy, I. L., Zabozlaev, F. G., Starodubova, E. S., Abakumova, T. O., Isaguliants, M. G., Chekhonin, V. P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5552689/
https://www.ncbi.nlm.nih.gov/pubmed/28798322
http://dx.doi.org/10.1038/s41598-017-07851-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5552689/
https://www.ncbi.nlm.nih.gov/pubmed/28798322
http://dx.doi.org/10.1038/s41598-017-07851-z

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