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Novel giardicidal compounds bearing proton pump inhibitor scaffold proceeding through triosephosphate isomerase inactivation

Giardiasis is a worldwide parasitic disease that affects mainly children and immunosuppressed people. Side effects and the emergence of resistance over current used drugs make imperative looking for new antiparasitics through discovering of new biological targets and designing of novel drugs. Recent...

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Detalles Bibliográficos
Autores principales: Hernández-Ochoa, B., Navarrete-Vázquez, G., Nava-Zuazo, C., Castillo-Villanueva, A., Méndez, S. T., Torres-Arroyo, A., Gómez-Manzo, S., Marcial-Quino, J., Ponce-Macotela, M., Rufino-González, Y., Martínez-Gordillo, M., Palencia-Hernández, G., Esturau-Escofet, N., Calderon-Jaimes, E., Oria-Hernández, J., Reyes-Vivas, H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5552691/
https://www.ncbi.nlm.nih.gov/pubmed/28798383
http://dx.doi.org/10.1038/s41598-017-07612-y