Cargando…
Novel giardicidal compounds bearing proton pump inhibitor scaffold proceeding through triosephosphate isomerase inactivation
Giardiasis is a worldwide parasitic disease that affects mainly children and immunosuppressed people. Side effects and the emergence of resistance over current used drugs make imperative looking for new antiparasitics through discovering of new biological targets and designing of novel drugs. Recent...
Autores principales: | Hernández-Ochoa, B., Navarrete-Vázquez, G., Nava-Zuazo, C., Castillo-Villanueva, A., Méndez, S. T., Torres-Arroyo, A., Gómez-Manzo, S., Marcial-Quino, J., Ponce-Macotela, M., Rufino-González, Y., Martínez-Gordillo, M., Palencia-Hernández, G., Esturau-Escofet, N., Calderon-Jaimes, E., Oria-Hernández, J., Reyes-Vivas, H. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5552691/ https://www.ncbi.nlm.nih.gov/pubmed/28798383 http://dx.doi.org/10.1038/s41598-017-07612-y |
Ejemplares similares
-
Disulfiram as a novel inactivator of Giardia lamblia triosephosphate isomerase with antigiardial potential
por: Castillo-Villanueva, Adriana, et al.
Publicado: (2017) -
Structural Effects of Protein Aging: Terminal Marking by Deamidation in Human Triosephosphate Isomerase
por: de la Mora-de la Mora, Ignacio, et al.
Publicado: (2015) -
Structural and Functional Perturbation of Giardia lamblia Triosephosphate Isomerase by Modification of a Non-Catalytic, Non-Conserved Region
por: Hernández-Alcántara, Gloria, et al.
Publicado: (2013) -
Gene Cloning, Recombinant Expression, Characterization, and Molecular Modeling of the Glycolytic Enzyme Triosephosphate Isomerase from Fusarium oxysporum
por: Hernández-Ochoa, Beatriz, et al.
Publicado: (2019) -
Species-Specific Inactivation of Triosephosphate Isomerase from Trypanosoma brucei: Kinetic and Molecular Dynamics Studies
por: Vázquez-Raygoza, Alejandra, et al.
Publicado: (2017)