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Anesthesia and Surgery Impair Blood–Brain Barrier and Cognitive Function in Mice

Blood–brain barrier (BBB) dysfunction, e.g., increase in BBB permeability, has been reported to contribute to cognitive impairment. However, the effects of anesthesia and surgery on BBB permeability, the underlying mechanisms, and associated cognitive function remain largely to be determined. Here,...

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Detalles Bibliográficos
Autores principales: Yang, Siming, Gu, Changping, Mandeville, Emiri T., Dong, Yuanlin, Esposito, Elga, Zhang, Yiying, Yang, Guang, Shen, Yuan, Fu, Xiaobing, Lo, Eng H., Xie, Zhongcong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5552714/
https://www.ncbi.nlm.nih.gov/pubmed/28848542
http://dx.doi.org/10.3389/fimmu.2017.00902