Studies on Colony Stimulating Factor Receptor-1 and Ligands Colony Stimulating Factor-1 and Interleukin-34 in Alzheimer's Disease Brains and Human Microglia

Microglia are dependent on signaling through the colony stimulating factor-1 receptor (CSF-1R/CD115) for growth and survival. Activation of CSF-1R can lead to cell division, while blocking CSF-1R can lead to rapid microglia cell death. CSF-1R has two ligands, the growth factors colony stimulating fa...

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Detalles Bibliográficos
Autores principales: Walker, Douglas G., Tang, Tiffany M., Lue, Lih-Fen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5552759/
https://www.ncbi.nlm.nih.gov/pubmed/28848420
http://dx.doi.org/10.3389/fnagi.2017.00244

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5552759/
https://www.ncbi.nlm.nih.gov/pubmed/28848420
http://dx.doi.org/10.3389/fnagi.2017.00244

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