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HIV-1 Tat-induced diarrhea evokes an enteric glia-dependent neuroinflammatory response in the central nervous system

Despite the effectiveness of combined anti-retroviral therapy, human immunodeficiency virus (HIV) infected-patients frequently report diarrhea and neuropsychological deficits. It is claimed that the viral HIV-1 Trans activating factor (HIV-1 Tat) protein is responsible for both diarrhea and neurotox...

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Detalles Bibliográficos
Autores principales: Esposito, Giuseppe, Capoccia, Elena, Gigli, Stefano, Pesce, Marcella, Bruzzese, Eugenia, D’Alessandro, Alessandra, Cirillo, Carla, di Cerbo, Alessandro, Cuomo, Rosario, Seguella, Luisa, Steardo, Luca, Sarnelli, Giovanni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5552820/
https://www.ncbi.nlm.nih.gov/pubmed/28798420
http://dx.doi.org/10.1038/s41598-017-05245-9