Analysis of Newly Identified and Rare Synonymous Genetic Variants in the RET Gene in Patients with Medullary Thyroid Carcinoma in Polish Population

Gain-of-function germline mutations of the RET proto-oncogene are responsible for initiation of carcinogenesis within the thyroid gland and development of hereditary form of medullary thyroid carcinoma and MEN2 syndrome. Genotype-phenotype correlations are established for most RET mutations, but the...

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Detalles Bibliográficos
Autores principales: Sromek, Maria, Czetwertyńska, Małgorzata, Tarasińska, Magdalena, Janiec-Jankowska, Aneta, Zub, Renata, Ćwikła, Maria, Nowakowska, Dorota, Chechlińska, Magdalena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5552825/
https://www.ncbi.nlm.nih.gov/pubmed/28647780
http://dx.doi.org/10.1007/s12022-017-9487-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5552825/
https://www.ncbi.nlm.nih.gov/pubmed/28647780
http://dx.doi.org/10.1007/s12022-017-9487-2

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