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Soluble epoxide hydrolase inhibition Promotes White Matter Integrity and Long-Term Functional Recovery after chronic hypoperfusion in mice

Chronic cerebral hypoperfusion induced cerebrovascular white matter lesions (WMLs) are closely associated with cognitive impairment and other neurological deficits. The mechanism of demyelination in response to hypoperfusion has not yet been fully clarified. Soluble epoxide hydrolase (sEH) is an end...

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Detalles Bibliográficos
Autores principales: Chen, Yuxue, Tian, Hao, Yao, Ensheng, Tian, Yeye, Zhang, Huaqiu, Xu, Li, Yu, Zhiyuan, Fang, Yongkang, Wang, Wei, Du, Peng, Xie, Minjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5552839/
https://www.ncbi.nlm.nih.gov/pubmed/28798352
http://dx.doi.org/10.1038/s41598-017-08227-z