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Phosphorylation of Serine 225 in Hepatitis C Virus NS5A Regulates Protein-Protein Interactions

Hepatitis C virus (HCV) nonstructural protein 5A (NS5A) is a phosphoprotein that plays key, yet poorly defined, roles in both virus genome replication and virion assembly/release. It has been proposed that differential phosphorylation could act as a switch to regulate the various functions of NS5A;...

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Detalles Bibliográficos
Autores principales: Goonawardane, Niluka, Gebhardt, Anna, Bartlett, Christopher, Pichlmair, Andreas, Harris, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5553161/
https://www.ncbi.nlm.nih.gov/pubmed/28615203
http://dx.doi.org/10.1128/JVI.00805-17