Monte Carlo simulations of randomized clinical trials in epilepsy

BACKGROUND: The placebo response in epilepsy randomized clinical trials (RCTs) has recently been shown to largely reflect underlying natural variability in seizure frequency. Based on this observation, we sought to explore the parameter space of RCT design to optimize trial efficiency and cost. METH...

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Detalles Bibliográficos
Autores principales: Goldenholz, Daniel M., Tharayil, Joseph, Moss, Robert, Myers, Evan, Theodore, William H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5553226/
https://www.ncbi.nlm.nih.gov/pubmed/28812044
http://dx.doi.org/10.1002/acn3.426

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5553226/
https://www.ncbi.nlm.nih.gov/pubmed/28812044
http://dx.doi.org/10.1002/acn3.426

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