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Aβ seeds and prions: How close the fit?

The prion paradigm is increasingly invoked to explain the molecular pathogenesis of neurodegenerative diseases involving the misfolding and aggregation of proteins other than the prion protein (PrP). Extensive evidence from in vitro and in vivo studies indicates that misfolded and aggregated Aβ pept...

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Detalles Bibliográficos
Autores principales: Rasmussen, Jay, Jucker, Mathias, Walker, Lary C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5553305/
https://www.ncbi.nlm.nih.gov/pubmed/28657440
http://dx.doi.org/10.1080/19336896.2017.1334029