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Expression optimization of a cell membrane-penetrating human papillomavirus type 16 therapeutic vaccine candidate in Nicotiana benthamiana

High-risk human papillomaviruses (hr-HPVs) cause cervical cancer, the fourth most common cancer in women worldwide. A HPV-16 candidate therapeutic vaccine, LALF(32-51)-E7, was developed by fusing a modified E7 protein to a bacterial cell-penetrating peptide (LALF): this elicited both tumour protecti...

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Detalles Bibliográficos
Autores principales: Yanez, Romana J. R., Lamprecht, Renate, Granadillo, Milaid, Weber, Brandon, Torrens, Isis, Rybicki, Edward P., Hitzeroth, Inga I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5553638/
https://www.ncbi.nlm.nih.gov/pubmed/28800364
http://dx.doi.org/10.1371/journal.pone.0183177