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Flavonolignans inhibit the arachidonic acid pathway in blood platelets

BACKGROUND: Arachidonic acid metabolism by cyclooxygenase (COX) is a major pathway for blood platelets’ activation, which is associated with pro-thrombotic platelet activity and the production of pro-inflammatory mediators. Inhibition of COX activity is one of the major means of anti-platelet pharma...

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Detalles Bibliográficos
Autores principales: Bijak, Michal, Saluk-Bijak, Joanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5553656/
https://www.ncbi.nlm.nih.gov/pubmed/28797264
http://dx.doi.org/10.1186/s12906-017-1897-7