A lowered 26S proteasome activity correlates with mantle lymphoma cell lines resistance to genotoxic stress

BACKGROUND: Mantle cell lymphoma (MCL) is a B-cell hemopathy characterized by the t(11;14) translocation and the aberrant overexpression of cyclin D1. This results in an unrestrained cell proliferation. Other genetic alterations are common in MCL cells such as SOX11 expression, mutations of ATM and/...

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Detalles Bibliográficos
Autores principales: Ben Younes, Khaoula, Body, Simon, Costé, Élodie, Viailly, Pierre-Julien, Miloudi, Hadjer, Coudre, Clémence, Jardin, Fabrice, Ben Aissa-Fennira, Fatma, Sola, Brigitte
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5553741/
https://www.ncbi.nlm.nih.gov/pubmed/28797244
http://dx.doi.org/10.1186/s12885-017-3530-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5553741/
https://www.ncbi.nlm.nih.gov/pubmed/28797244
http://dx.doi.org/10.1186/s12885-017-3530-z

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