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Angiopoietin-1 deficiency increases tumor metastasis in mice
BACKGROUND: Angipoietin-1 activation of the tyrosine kinase receptor Tek expressed mainly on endothelial cells leads to survival and stabilization of endothelial cells. Studies have shown that Angiopoietin-1 counteracts permeability induced by a number of stimuli. Here, we test the hypothesis that l...
Autores principales: | Michael, Iacovos P., Orebrand, Martina, Lima, Marta, Pereira, Beatriz, Volpert, Olga, Quaggin, Susan E., Jeansson, Marie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5553747/ https://www.ncbi.nlm.nih.gov/pubmed/28800750 http://dx.doi.org/10.1186/s12885-017-3531-y |
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