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The adaptive landscape of wildtype and glycosylation-deficient populations of the industrial yeast Pichia pastoris

BACKGROUND: The effects of long-term environmental adaptation and the implications of major cellular malfunctions are still poorly understood for non-model but biotechnologically relevant species. In this study we performed a large-scale laboratory evolution experiment with 48 populations of the yea...

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Detalles Bibliográficos
Autores principales: Moser, Josef W., Wilson, Iain B. H., Dragosits, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5553748/
https://www.ncbi.nlm.nih.gov/pubmed/28797224
http://dx.doi.org/10.1186/s12864-017-3952-7