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Highly efficient gene inactivation by adenoviral CRISPR/Cas9 in human primary cells
Phenotypic assays using human primary cells are highly valuable tools for target discovery and validation in drug discovery. Expression knockdown (KD) of such targets in these assays allows the investigation of their role in models of disease processes. Therefore, efficient and fast modes of protein...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5553774/ https://www.ncbi.nlm.nih.gov/pubmed/28800587 http://dx.doi.org/10.1371/journal.pone.0182974 |