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Targeting lysyl oxidase reduces peritoneal fibrosis

BACKGROUND: Abdominal surgery and disease cause persistent abdominal adhesions, pelvic pain, infertility and occasionally, bowel obstruction. Current treatments are ineffective and the aetiology is unclear, although excessive collagen deposition is a consistent feature. Lysyl oxidase (Lox) is a key...

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Detalles Bibliográficos
Autores principales: Harlow, Christopher R., Wu, Xuan, van Deemter, Marielle, Gardiner, Fiona, Poland, Craig, Green, Rebecca, Sarvi, Sana, Brown, Pamela, Kadler, Karl E., Lu, Yinhui, Mason, J. Ian, Critchley, Hilary O. D., Hillier, Stephen G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5553776/
https://www.ncbi.nlm.nih.gov/pubmed/28800626
http://dx.doi.org/10.1371/journal.pone.0183013