Membrane localization of acetylated CNK1 mediates a positive feedback on RAF/ERK signaling

Spatiotemporal control is a common mechanism that modulates activity and function of signal transducers in the signaling network. We identified acetylation of CNK1 (connector enhancer of kinase suppressor of Ras-1) as a late step in the activation of CNK1 signaling, accompanied with prolonged stimul...

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Detalles Bibliográficos
Autores principales: Fischer, Adrian, Mühlhäuser, Wignand W. D., Warscheid, Bettina, Radziwill, Gerald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5553820/
https://www.ncbi.nlm.nih.gov/pubmed/28819643
http://dx.doi.org/10.1126/sciadv.1700475

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5553820/
https://www.ncbi.nlm.nih.gov/pubmed/28819643
http://dx.doi.org/10.1126/sciadv.1700475

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