Structure and reconstitution of yeast Mpp6-nuclear exosome complexes reveals that Mpp6 stimulates RNA decay and recruits the Mtr4 helicase

Nuclear RNA exosomes catalyze a range of RNA processing and decay activities that are coordinated in part by cofactors, including Mpp6, Rrp47, and the Mtr4 RNA helicase. Mpp6 interacts with the nine-subunit exosome core, while Rrp47 stabilizes the exoribonuclease Rrp6 and recruits Mtr4, but it is le...

Descripción completa

Detalles Bibliográficos
Autores principales: Wasmuth, Elizabeth V, Zinder, John C, Zattas, Dimitrios, Das, Mom, Lima, Christopher D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Biochemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5553935/
https://www.ncbi.nlm.nih.gov/pubmed/28742025
http://dx.doi.org/10.7554/eLife.29062

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5553935/
https://www.ncbi.nlm.nih.gov/pubmed/28742025
http://dx.doi.org/10.7554/eLife.29062

Ejemplares similares