T cell receptor repertoires of mice and humans are clustered in similarity networks around conserved public CDR3 sequences

Diversity of T cell receptor (TCR) repertoires, generated by somatic DNA rearrangements, is central to immune system function. However, the level of sequence similarity of TCR repertoires within and between species has not been characterized. Using network analysis of high-throughput TCR sequencing...

Descripción completa

Detalles Bibliográficos
Autores principales: Madi, Asaf, Poran, Asaf, Shifrut, Eric, Reich-Zeliger, Shlomit, Greenstein, Erez, Zaretsky, Irena, Arnon, Tomer, Laethem, Francois Van, Singer, Alfred, Lu, Jinghua, Sun, Peter D, Cohen, Irun R, Friedman, Nir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Computational and Systems Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5553937/
https://www.ncbi.nlm.nih.gov/pubmed/28731407
http://dx.doi.org/10.7554/eLife.22057

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5553937/
https://www.ncbi.nlm.nih.gov/pubmed/28731407
http://dx.doi.org/10.7554/eLife.22057

Ejemplares similares