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The Cumulative Effects of Known Susceptibility Variants to Predict Primary Biliary Cirrhosis Risk

Multiple genetic variants influence the risk for development of primary biliary cirrhosis (PBC). To explore the cumulative effects of known susceptibility loci on risk, we utilized a weighted genetic risk score (wGRS) to evaluate whether genetic information can predict susceptibility. The wGRS was c...

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Detalles Bibliográficos
Autores principales: Tang, Ruqi, Chen, Haoyan, Miao, Qi, Bian, Zhaolian, Ma, Wansu, Feng, Xiaomei, Seldin, Michael F., Invernizzi, Pietro, Gershwin, M. Eric, Liao, Wilson, Ma, Xiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5553973/
https://www.ncbi.nlm.nih.gov/pubmed/25569263
http://dx.doi.org/10.1038/gene.2014.76