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Limits of radiomic-based entropy as a surrogate of tumor heterogeneity: ROI-area, acquisition protocol and tissue site exert substantial influence

Entropy is a promising quantitative imaging biomarker for characterizing cancer imaging phenotype. Entropy has been associated with tumor gene expression, tumor metabolism, tumor stage, patient prognosis, and treatment response. Our hypothesis states that tumor-specific biomarkers such as entropy sh...

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Detalles Bibliográficos
Autores principales: Dercle, Laurent, Ammari, Samy, Bateson, Mathilde, Durand, Paul Blanc, Haspinger, Eva, Massard, Christophe, Jaudet, Cyril, Varga, Andrea, Deutsch, Eric, Soria, Jean-Charles, Ferté, Charles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5554130/
https://www.ncbi.nlm.nih.gov/pubmed/28801575
http://dx.doi.org/10.1038/s41598-017-08310-5